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The Anti-Aging Power of NAD+ Therapy

December 12, 2023

As we age, our levels of a crucial cellular compound called NAD+ decline. This drop impacts everything from energy levels to DNA repair. But replenishing NAD+ though intravenous therapy may hold the key to slowing aging and staying healthy. Here’s what you need to know about NAD+ and its anti-aging potential.

What is NAD+?

NAD+, or nicotinamide adenine dinucleotide, acts as a coenzyme in cellular energy production and DNA maintenance. It plays a role in hundreds of biochemical reactions responsible for youthfulness. As we get older, our bodies produce less NAD+. This leads to a decline in cellular health over decades.

Specifically, NAD+ is needed to:

  • Generate new ATP energy molecules within mitochondria
  • Activate sirtuin proteins involved in DNA protection, stress response and inflammation control
  • Break down lactate and pyruvate for use in the citric acid cycle
  • Support neurotransmitter synthesis

When NAD+ levels fall, our cells struggle to produce energy, repair DNA damage and communicate properly. This cascades into issues like weight gain, cognitive decline and disease susceptibility.

Benefits of NAD+ Therapy

Research shows restoring NAD+ levels via IV therapy may help counter premature aging. Here are some potential anti-aging benefits:

  • Increased Energy: Early studies link NAD+ injections to improved mitochondrial ATP production and lower fatigue levels.
  • Enhanced DNA Repair: Animal research finds NAD+ therapy boosts activity of DNA repair proteins and reduces DNA damage accumulation typically seen with aging.
  • Reduced Inflammation: NAD+ activates pathways related to chronic inflammation control. This antioxidant effect may ward off age-related disease processes.
  • Neuroprotection: Studies link NAD+ replenishment to neural insulin sensitivity, neurotransmitter levels and neuron survival – all important for brain health as we age.
  • Cellular Renewal: By supporting sirtuins involved in recycling processes like autophagy, NAD+ may enhance the regeneration of new, healthy cells over damaged ones.
  • Weight Management: Early evidence indicates NAD+ injections regulate appetite, enhance fat burning and improve metabolic flexibility for easier weight maintenance or loss.

How It Works

During IV NAD+ therapy, a solution of nicotinamide riboside or nicotinamide mononucleotide (NR or NMN) is administered through a peripheral IV line over 60-90 minutes. These precursors are quickly converted to NAD+ within cells. One or twice weekly sessions are typically recommended for a treatment series of 10-20 administrations. This allows the mitochondria and DNA repair systems time to benefit from incremental NAD+ boosts. Results may include increased energy levels, physical endurance and mental clarity.

Research on the effects of NAD+ therapy in humans is still emerging but early results have been promising. As therapeutic use grows, we can expect better understanding of its anti-aging potential and role as a cellular health promoter. For now, NAD+ holds exciting implications in prevention of conditions like Alzheimer’s disease, Parkinson’s disease, diabetes and heart disease simply by combating the root causes of aging itself.


Adding medically-supervised IV NAD+ treatments could complement an already healthy lifestyle focused on nutrition, stress management and exercise. By restoring your body’s natural production of this vital coenzyme, you may be able to stay mentally sharp, physically active and disease-resistant well into your senior years. Consider NAD+ therapy if you’re committed to slow, healthy aging and want the latest biohacking tools technology has to offer. With continued research, stay tuned for new insights into this innovative anti-aging approach.